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The Portable Neuromodulation Stimulator (PoNS™) Device


The Portable Neuromodulation Stimulator (PoNS™) is an authorized medical device in the United States. The PoNS device is indicated for use as a short term treatment of gait deficit due to mild-to-moderate symptoms from multiple sclerosis (“MS”) and is to be used as an adjunct to a supervised therapeutic exercise program in patients 22 years of age and over by prescription only.

PoNS is authorized for sale in Canada as a class II, non-implantable, medical device intended as a short term treatment (14 weeks) of gait deficit due to mild and moderate symptoms from multiple sclerosis (MS), and chronic balance deficit due to mild-to-moderate traumatic brain injury (mmTBI) and is to be used in conjunction with physical therapy.

While physicians and patients turn to available options to manage a host of neurological symptoms today, limited options actually help rehabilitate lost functions for the millions of people living with chronic disorders. The PoNS device is being studied as a new potential option for the treatment of chronic neurological symptoms of disease or trauma.

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PoNS Scientists

This novel way to apply the concept of neuroplasticity to rehabilitation is the brainchild of scientists at the University of Wisconsin-Madison Tactile Communication and Neurorehabilitation Laboratory (TCNL).

Scientific Theory: Amplifying the Brain’s Ability to Heal Itself

The PoNS device is based on almost 40 years of research in the field of neuromodulation—the use of external stimulation to intentionally change and regulate the electrochemical environment of the brain. It is believed that neuromodulation enhances neuroplasticity, the brain’s ability to restructure or relearn in response to new experiences, sensory input, and functional demands. Research has shown that the process of neuroplasticity underlies all cerebral learning, training and rehabilitation.

In clinical studies, the PoNS device coupled with targeted functional therapy (together PoNS® Treatment) induces neuroplasticity. Therapy consists of targeted physical, occupational and cognitive exercises, based on the patient’s deficits.

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Research shows that electrical stimulation of the tongue (translingual neurostimulation – TLNS) stimulates two major cranial nerves: the trigeminal (the nerve responsible for sensations in the face, biting and chewing) and the facial (the nerve responsible for motor control of most of the muscles of facial expression). The electrical stimulation of the cranial nerves creates a flow of neural impulses that are then delivered directly into the brain stem—the main control center for many life functions, including sensory perception and movement. From the brain stem, these impulses travel throughout the brain and activate or reactivate neurons and structures involved in human function—the cortex, spinal cord and potentially the entire central nervous system.

Researchers believe that this sustained stimulation initiates a sequential cascade of changes in the actual interconnected nuclei, or the neuronal network, that are at the core of major anatomical components of the brain.

Based on this theory, it is believed that neuromodulation induced by the PoNS device, combined with functional therapy, may be applied to improve a large variety of neurological symptoms. For more detailed information, download the PoNS fact sheet from the Media Resources page.